Laboratoriyalar
Laboratories Catalog
7 fundamental and applied research departments of the Institute of Biophysics and Biochemistry
Cell Biophysics
Cellular Biophysics Laboratory
The Cellular Biophysics Laboratory studies transport mechanisms at the cellular level and the role of exosomes.
Main research directions
Familiarization with the laboratory
Neyrotoksinlar ta'siri
NMDA retseptorlari
Bioinsektitsidlar
Kardioproteksiya
Electrophysiology
Electrophysiology Laboratory
The electrophysiology laboratory studies the electrical properties of ion channels using the patch-clamp method.
Main research directions
Familiarization with the laboratory
Qon tomir silliq mushaklari
Gemostaz va koagulyatsiya
Gyurza zaxari fraksiyalari
Neyroprotektor moddalar
Genomics
Genomics Laboratory
The Genomics Laboratory studies the genetic basis of diseases and drug resistance.
Main research directions
Familiarization with the laboratory
Identification of polymorphisms of marker genes of various diseases.
Study of candidate gene polymorphisms associated with multidrug resistance involved in drug metabolism.
Development of regional molecular-genetic test systems for disease diagnosis and pharmacotherapy.
Diagnosis of drug resistance level and genetic testing by polymorphic marker gene in oncological diseases.
Membrane Biophysics
Membrane Biophysics Laboratory
The Membrane Biophysics Laboratory studies ion channels in cell membranes and their role in diseases.
Main research directions
Familiarization with the laboratory
Biofizikaning asosiy fundamental muammolari va fiziologik faol moddalarni (gormonlar, yurak glikozidlari, hayvon va o‘simlik toksinlari, pestitsidlar, hasharotlar feromonlari va boshqa membrana faol birikmalar) membranalar funksiyasi regulyatsiyasi va biofizik mexanizmlariga ta’sirini o‘rganish.
Membranalar orqali faol ion transportining biofizik mexanizmlarini o‘rganish. Akad. B.A. Tashmuxamedov rahbarligida va bevosita ishtirokida membranologiyaning amaliy bo‘limi – sun’iy ionoforlar yo‘nalishi tashkil etildi (ionselektiv elektrodlar, eritmalardan ionlarni ajratish).
Fitoxrom va boshqa o‘simliklar fotoretseptorlarida fotoregulyator tizimlari hamda fiziologik jarayonlarni regulyatsiya qilish jarayonlarini o‘rganish. O‘simliklarda fitoxrom faolligiga ta’sir etuvchi mutatsiyalar va tashqi muhitning salbiy oqibatlariga chidamliligi tadqiq etilmoqda.
Hujayralar ion kanallari va model membranalar orqali ion transport mexanizmlarining fundamental muammolari bilan shug‘ullanish.
Metabolomics
Metabolomics Laboratory
The metabolomics laboratory studies changes in metabolites in cells on a large scale.
Main research directions
Familiarization with the laboratory
Lipidlar almashinuvi
Tiroksin gormonlari
Diabet patogenezi
Liposomal preparatlar
Molecular Biophysics
Molecular Biophysics Laboratory
The Molecular Biophysics Laboratory studies the structure and function of proteins and nucleotides at the molecular level.
Main research directions
Familiarization with the laboratory
Mitoxondriya membranasi orqali ionlar va metabolitlar tashilishining molekular mexanizmlarini o‘rganish.
Organizmga biologik faol birikmalarning (o‘simlik preparatlari, ksenobiotiklar, dorivor vositalar) mitoxondriya funksional parametrlariga ta’sir mexanizmlarini o‘rganish.
Turli patologik holatlarda mitoxondriya membranalaridagi funksional o‘zgarishlarni o‘rganish, patologiyadagi membranaviy buzilishlarni o‘simlik moddalari yordamida korreksiya qilish.
Molecular Physiology
Molecular Physiology Laboratory
The Molecular Physiology Laboratory studies molecular processes in the nervous system and cardiovascular diseases.
Main research directions
Familiarization with the laboratory
Hujayra membranalarining ion kanallari orqali ion transporti mexanizmining asosiy muammolari, ion kanallarining tuzilish va funksional munosabatlari va hujayra fiziologiyasi hamda patofiziologiyasining molekular asoslarini o‘rganish.
Elektrofiziologik usullar bilan endogen ion kanallarini va tabiiy hujayralar membranalarida transporterlarni aniqlash.
Hujayra hajmini boshqarish tizimi, biofizik xususiyatlar, molekular tabiat hamda hajmga bog‘liq anion kanallarining hujayra fiziologik jarayonlaridagi rolini tadqiq etish.
Tashqariga yo‘nalgan anion kanallari va yuqori o‘tkazuvchanlikka ega potensialga bog‘liq anion kanallari xususiyatlarini o‘rganish.